Rich Haridy, writing for New Atlas:
For the last few years psychiatrist Ben Sessa and a team of UK researchers have been exploring the role of MDMA therapy in treating alcohol use disorder (AUD). In a newly published study the researchers report on the world’s first trial testing the novel treatment on patients suffering from addiction.
This small, proof-of-concept study recruited 14 subjects with AUD. The goal of this preliminary study was to establish a safety profile for the MDMA therapy in patients suffering from AUD, but an expansive nine-month follow-up period also allowed for a unique insight into the possible long-term efficacy of the treatment. […]
In regards to tolerability and safety, the study reports no adverse responses to the drug were detected either during a treatment session or in the days following. In a fascinating side note, the study followed each subject’s acute mood state for seven days after each MDMA session. […]
Nine months after the trial only 21 percent of the cohort were drinking more than 14 units of alcohol per week. This compares to an average of 130 units of alcohol consumed per week by each patient before detox at the beginning of the study.
Impressive results from this first-of-its-kind study. And although this wasn’t a placebo-controlled trial, the researchers also conducted an additional study that explored how MDMA therapy compares to standard treatments for alcohol addiction:
Fourteen subjects were recruited and tracked for nine months following detox for this adjacent outcome study. A striking 75 percent were consuming more than 14 units of alcohol per week at the nine-month follow-up point. This data resembles the generally poor long-term outcomes for current AUD treatments, which register drinking relapse rates at around 60 percent one year after treatment and 80 percent three years later.
Not too shabby.